Info
| ID | 5856 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 3} |
| Abbreviation | 1 |
| SMILES | Cc1c(C)c(C)[c-](C)c1C.[Cl-].[c-]1cccc2c1c1ncccc1c1nc3ccccc3nc21 |
TUCAN
C29H25IrN3/(1-26)(2-26)(3-26)(4-27)(5-27)(6-40)(7-38)(8-37)(9-33)(10-36)(11-32)(12-39)(13-35)(14-34)(15-49)(16-27)(17-28)(18-28)(19-28)(20-29)(21-29)(22-29)(23-30)(24-30)(25-30)(26-42)(27-43)(28-44)(29-45)(30-46)(31-33)(31-47)(32-38)(32-50)(33-37)(34-36)(34-38)(35-37)(35-41)(36-54)(39-40)(39-48)(40-49)(41-47)(41-52)(42-43)(42-44)(43-45)(44-46)(45-46)(47-51)(48-51)(48-53)(49-56)(50-54)(50-55)(51-56)(52-53)(52-55)(53-57)(54-57)(56-58)(57-58)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 8 | 2.9 | 10.1021/acs.jmedchem.3c01276 | 2024 |
| A549 | 8 | 5.8 | 10.1021/acs.jmedchem.3c01276 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Consequently, cell death by apoptosis and secondary necrosis is activated.»