Info
| ID | 5819 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 7} |
| Abbreviation | YQ4 |
| SMILES | CN(C)c1ccc(/C=C/c2nc3c4cccnc4c4ncccc4c3[nH]2)cc1.[c-]1ccccc1-c1nccc2ccccc12.[c-]1ccccc1-c1nccc2ccccc12 |
TUCAN
C53H39IrN7/(1-61)(2-81)(3-45)(4-63)(5-47)(6-44)(7-57)(8-54)(9-42)(10-66)(11-43)(12-83)(13-49)(14-79)(15-79)(16-79)(17-80)(18-80)(19-80)(20-50)(21-51)(22-67)(23-84)(24-53)(25-48)(26-55)(27-46)(28-68)(29-69)(30-59)(31-82)(32-52)(33-62)(34-65)(35-64)(36-56)(37-60)(38-58)(39-94)(40-54)(40-70)(41-66)(41-71)(42-44)(42-48)(43-47)(43-70)(44-72)(45-48)(45-74)(46-56)(46-62)(47-57)(49-55)(49-71)(50-51)(50-77)(51-88)(52-53)(52-78)(53-82)(54-57)(55-64)(56-65)(58-69)(58-77)(59-67)(59-84)(60-68)(60-77)(61-74)(61-81)(62-75)(63-76)(63-83)(64-66)(65-76)(67-73)(68-88)(69-92)(70-85)(71-86)(72-74)(72-85)(73-87)(73-91)(75-76)(75-86)(78-89)(78-90)(79-95)(80-95)(81-96)(82-93)(83-99)(84-98)(85-96)(86-99)(87-89)(87-97)(88-95)(89-94)(90-91)(90-93)(91-98)(92-94)(92-97)(96-100)(97-100)(98-100)(99-100)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A375 | — | 0.83 | 10.1021/acs.inorgchem.3c02364 | 2023 |
| A549 | — | 0.91 | 10.1021/acs.inorgchem.3c02364 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«YQ2 could enter cells ... activate caspases, and induce apoptosis.»