Info
| ID | 5816 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 6} |
| Abbreviation | YQ1 |
| SMILES | C(=C/c1nc2c3cccnc3c3ncccc3c2[nH]1)\c1ccccc1.[c-]1ccccc1-c1nccc2ccccc12.[c-]1ccccc1-c1nccc2ccccc12 |
TUCAN
C51H34IrN6/(1-40)(2-51)(3-54)(4-42)(5-75)(6-41)(7-38)(8-44)(9-78)(10-39)(11-62)(12-55)(13-64)(14-63)(15-76)(16-77)(17-46)(18-57)(19-43)(20-60)(21-37)(22-61)(23-58)(24-45)(25-50)(26-47)(27-48)(28-65)(29-59)(30-52)(31-53)(32-49)(33-56)(34-87)(35-43)(35-69)(36-60)(36-73)(37-38)(37-41)(38-40)(39-66)(39-75)(40-71)(41-66)(42-44)(42-51)(43-44)(45-49)(45-74)(46-47)(46-48)(47-70)(48-57)(49-76)(50-64)(50-68)(51-69)(52-59)(52-61)(53-58)(53-60)(54-61)(54-72)(55-67)(55-78)(56-63)(56-85)(57-65)(58-62)(59-67)(62-73)(63-70)(64-77)(65-70)(66-71)(67-72)(68-79)(68-81)(69-80)(71-80)(72-83)(73-83)(74-82)(74-84)(75-88)(76-86)(77-91)(78-89)(79-82)(79-90)(80-88)(81-84)(81-91)(82-87)(83-89)(84-86)(85-87)(85-90)(88-92)(89-92)(90-92)(91-92)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A375 | — | 1.1 | 10.1021/acs.inorgchem.3c02364 | 2023 |
| A549 | — | 1.2 | 10.1021/acs.inorgchem.3c02364 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«YQ2 could enter cells ... activate caspases, and induce apoptosis.»