Info
| ID | 5815 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 7} |
| Abbreviation | YP4 |
| SMILES | CN(C)c1ccc(/C=C/c2nc3c4cccnc4c4ncccc4c3[nH]2)cc1.[c-]1ccccc1-c1ccc2ccccc2n1.[c-]1ccccc1-c1ccc2ccccc2n1 |
TUCAN
C53H39IrN7/(1-44)(2-47)(3-54)(4-42)(5-58)(6-46)(7-55)(8-57)(9-48)(10-66)(11-43)(12-45)(13-67)(14-59)(15-68)(16-79)(17-79)(18-79)(19-80)(20-80)(21-71)(22-61)(23-69)(24-82)(25-51)(26-70)(27-56)(28-63)(29-64)(30-80)(31-60)(32-81)(33-50)(34-62)(35-53)(36-52)(37-49)(38-65)(39-94)(40-57)(40-72)(41-66)(41-73)(42-48)(42-54)(43-47)(43-72)(44-45)(44-74)(45-83)(46-54)(46-85)(47-55)(48-74)(49-58)(49-73)(50-51)(50-76)(51-81)(52-63)(52-77)(53-64)(53-90)(55-57)(56-65)(56-77)(58-67)(59-68)(59-78)(60-69)(60-82)(61-71)(61-78)(62-70)(62-78)(63-84)(64-65)(66-67)(68-88)(69-75)(70-88)(71-92)(72-83)(73-84)(74-85)(75-87)(75-91)(76-86)(76-89)(77-90)(79-95)(80-95)(81-93)(82-99)(83-96)(84-98)(85-96)(86-87)(86-94)(87-97)(88-95)(89-91)(89-93)(90-98)(91-99)(92-94)(92-97)(96-100)(97-100)(98-100)(99-100)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A375 | — | 1.4 | 10.1021/acs.inorgchem.3c02364 | 2023 |
| A549 | — | 1.3 | 10.1021/acs.inorgchem.3c02364 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«YQ2 could enter cells ... activate caspases, and induce apoptosis.»