Info
| ID | 5812 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 6} |
| Abbreviation | YP1 |
| SMILES | C(=C/c1nc2c3cccnc3c3ncccc3c2[nH]1)\c1ccccc1.[c-]1ccccc1-c1ccc2ccccc2n1.[c-]1ccccc1-c1ccc2ccccc2n1 |
TUCAN
C51H34IrN6/(1-56)(2-61)(3-46)(4-42)(5-40)(6-49)(7-44)(8-57)(9-39)(10-60)(11-64)(12-75)(13-65)(14-50)(15-54)(16-51)(17-59)(18-62)(19-38)(20-37)(21-47)(22-43)(23-76)(24-55)(25-52)(26-53)(27-67)(28-63)(29-48)(30-41)(31-45)(32-66)(33-58)(34-87)(35-38)(35-70)(36-47)(36-73)(37-41)(37-61)(38-44)(39-42)(39-68)(40-41)(40-68)(42-80)(43-45)(43-63)(44-46)(45-49)(46-56)(47-48)(48-62)(49-71)(50-54)(50-74)(51-52)(51-53)(52-72)(53-59)(54-75)(55-66)(55-69)(56-70)(57-64)(57-83)(58-65)(58-85)(59-67)(60-62)(60-73)(61-78)(63-79)(64-71)(65-72)(66-76)(67-72)(68-78)(69-77)(69-82)(70-80)(71-79)(73-83)(74-81)(74-84)(75-86)(76-91)(77-81)(77-88)(78-89)(79-90)(80-89)(81-87)(82-84)(82-91)(83-90)(84-86)(85-87)(85-88)(88-92)(89-92)(90-92)(91-92)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A375 | — | 1.9 | 10.1021/acs.inorgchem.3c02364 | 2023 |
| A549 | — | 1.7 | 10.1021/acs.inorgchem.3c02364 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«YQ2 could enter cells ... activate caspases, and induce apoptosis.»