Info
| ID | 5811 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 7} |
| Abbreviation | YF4 |
| SMILES | CN(C)c1ccc(/C=C/c2nc3c4cccnc4c4ncccc4c3[nH]2)cc1.Fc1c[c-]c(-c2ccccn2)c(F)c1.Fc1c[c-]c(-c2ccccn2)c(F)c1 |
TUCAN
C45H31F4IrN7/(1-37)(2-42)(3-43)(4-52)(5-34)(6-48)(7-39)(8-38)(9-36)(10-35)(11-63)(12-51)(13-61)(14-44)(15-59)(16-59)(17-47)(18-59)(19-41)(20-40)(21-45)(22-46)(23-60)(24-50)(25-60)(26-53)(27-60)(28-62)(29-49)(30-64)(31-78)(32-36)(32-54)(33-49)(33-58)(34-38)(34-68)(35-38)(35-61)(36-75)(37-73)(37-75)(39-40)(39-55)(40-62)(41-42)(41-66)(42-57)(43-52)(43-57)(44-53)(44-57)(45-50)(45-70)(46-74)(46-76)(47-50)(47-64)(48-51)(48-63)(49-76)(51-56)(52-72)(53-66)(54-68)(54-73)(55-65)(55-71)(56-67)(56-69)(58-70)(58-74)(59-79)(60-79)(61-80)(62-77)(63-83)(64-82)(65-67)(65-78)(66-79)(67-81)(68-80)(69-71)(69-83)(70-82)(71-77)(72-78)(72-81)(73-84)(74-87)(75-85)(76-86)(80-88)(81-88)(82-88)(83-88)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A375 | — | 1.1 | 10.1021/acs.inorgchem.3c02364 | 2023 |
| A549 | — | 0.83 | 10.1021/acs.inorgchem.3c02364 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«YQ2 could enter cells ... activate caspases, and induce apoptosis.»