Info
| ID | 5810 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 6} |
| Abbreviation | YF3 |
| SMILES | COc1ccc(/C=C/c2nc3c4cccnc4c4ncccc4c3[nH]2)cc1.Fc1c[c-]c(-c2ccccn2)c(F)c1.Fc1c[c-]c(-c2ccccn2)c(F)c1 |
TUCAN
C44H28F4IrN6O/(1-44)(2-47)(3-40)(4-31)(5-58)(6-46)(7-32)(8-59)(9-39)(10-35)(11-42)(12-67)(13-45)(14-67)(15-34)(16-36)(17-37)(18-50)(19-33)(20-48)(21-49)(22-67)(23-56)(24-38)(25-43)(26-41)(27-57)(28-74)(29-31)(29-51)(30-33)(30-53)(31-69)(32-35)(32-44)(33-70)(34-69)(34-71)(35-56)(36-37)(36-68)(37-52)(38-43)(38-52)(39-47)(39-58)(40-42)(40-52)(41-50)(41-59)(42-66)(43-68)(44-63)(45-49)(45-57)(46-49)(46-64)(47-55)(48-70)(48-72)(50-54)(51-63)(51-71)(53-64)(53-72)(54-61)(54-62)(55-60)(55-65)(56-75)(57-78)(58-76)(59-73)(60-61)(60-77)(61-74)(62-65)(62-73)(63-75)(64-78)(65-76)(66-74)(66-77)(67-79)(68-79)(69-80)(70-81)(71-82)(72-83)(75-84)(76-84)(77-84)(78-84)(79-84)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A375 | — | 0.84 | 10.1021/acs.inorgchem.3c02364 | 2023 |
| A549 | — | 0.97 | 10.1021/acs.inorgchem.3c02364 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«YQ2 could enter cells ... activate caspases, and induce apoptosis.»
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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