Info
| ID | 5809 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 6, "O": 1} |
| Abbreviation | YF2 |
| SMILES | Fc1c[c-]c(-c2ccccn2)c(F)c1.Fc1c[c-]c(-c2ccccn2)c(F)c1.O=[N+]([O-])c1ccc(/C=C/c2nc3c4cccnc4c4ncccc4c3[nH]2)cc1 |
TUCAN
C43H25F4IrN7O2/(1-34)(2-35)(3-28)(4-30)(5-33)(6-38)(7-41)(8-29)(9-44)(10-36)(11-46)(12-54)(13-43)(14-40)(15-53)(16-42)(17-55)(18-39)(19-31)(20-32)(21-47)(22-37)(23-56)(24-45)(25-70)(26-33)(26-51)(27-47)(27-52)(28-36)(28-59)(29-34)(29-60)(30-34)(30-54)(31-35)(31-55)(32-37)(32-59)(33-65)(35-50)(36-48)(37-48)(38-65)(38-67)(39-46)(39-56)(40-44)(40-48)(41-43)(41-49)(42-66)(42-68)(43-53)(44-64)(45-46)(45-63)(47-66)(49-58)(49-61)(50-57)(50-62)(51-60)(51-67)(52-63)(52-68)(53-69)(54-73)(55-74)(56-75)(57-58)(57-72)(58-70)(59-71)(60-73)(61-62)(61-69)(62-74)(63-75)(64-70)(64-72)(65-78)(66-81)(67-79)(68-80)(71-76)(71-77)(72-82)(73-82)(74-82)(75-82)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A375 | — | 0.73 | 10.1021/acs.inorgchem.3c02364 | 2023 |
| A549 | — | 0.61 | 10.1021/acs.inorgchem.3c02364 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«YQ2 could enter cells ... activate caspases, and induce apoptosis.»