Info
| ID | 5808 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 6} |
| Abbreviation | YF1 |
| SMILES | C(=C/c1nc2c3cccnc3c3ncccc3c2[nH]1)\c1ccccc1.Fc1c[c-]c(-c2ccccn2)c(F)c1.Fc1c[c-]c(-c2ccccn2)c(F)c1 |
TUCAN
C43H26F4IrN6/(1-32)(2-43)(3-41)(4-57)(5-29)(6-39)(7-44)(8-31)(9-49)(10-42)(11-55)(12-30)(13-56)(14-34)(15-46)(16-33)(17-38)(18-40)(19-47)(20-45)(21-36)(22-35)(23-48)(24-37)(25-58)(26-71)(27-29)(27-50)(28-38)(28-53)(29-68)(30-33)(30-56)(31-32)(31-54)(32-49)(33-52)(34-35)(34-54)(35-65)(36-43)(36-46)(37-44)(37-47)(38-69)(39-66)(39-68)(40-48)(40-51)(41-42)(41-49)(42-54)(43-59)(44-60)(45-67)(45-69)(46-57)(47-58)(48-55)(50-59)(50-66)(51-63)(51-64)(52-61)(52-62)(53-60)(53-67)(55-70)(56-74)(57-72)(58-73)(59-72)(60-73)(61-64)(61-74)(62-63)(62-75)(63-71)(64-70)(65-71)(65-75)(66-76)(67-79)(68-77)(69-78)(72-80)(73-80)(74-80)(75-80)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A375 | — | 1.5 | 10.1021/acs.inorgchem.3c02364 | 2023 |
| A549 | — | 1.8 | 10.1021/acs.inorgchem.3c02364 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«YQ2 could enter cells ... activate caspases, and induce apoptosis.»