Info
| ID | 580 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | Ru7 |
| SMILES | CC(C)c1cccc(C(C)C)c1/N=C/c1ccccc1N.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C29ClN2Ru/(1-24)(2-25)(3-25)(4-24)(5-21)(6-26)(7-26)(8-9)(8-14)(9-20)(10-11)(10-21)(11-23)(12-18)(12-23)(13-15)(13-19)(14-22)(15-16)(16-17)(17-28)(18-21)(19-27)(19-28)(20-24)(20-29)(22-26)(22-29)(23-25)(27-31)(28-30)(29-31)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 6 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| A549 | 6.3 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| A549cisR | 8.5 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| HepG2 | 12 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| BEAS-2B | 22 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«Further, the induction of cell apoptosis and the perturbation of the cell cycle in the G0/G1 phase were also observed for these complexes.»