Info
| ID | 5793 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 4, "O": 1} |
| Abbreviation | B2 |
| SMILES | Cc1cc(-c2[c-]c3ccccc3s2)nc2ccccc12.Cc1cc(-c2[c-]c3ccccc3s2)nc2ccccc12.O=C([O-])c1ncccc1OCCCN1CCOCC1 |
TUCAN
C49H41IrN4O4S2/(1-48)(2-66)(3-52)(4-42)(5-84)(6-75)(7-75)(8-46)(9-42)(10-42)(11-60)(12-43)(13-53)(14-66)(15-58)(16-49)(17-84)(18-76)(19-76)(20-51)(21-43)(22-43)(23-65)(24-82)(25-47)(26-82)(27-74)(28-64)(29-50)(30-55)(31-83)(32-74)(33-73)(34-83)(35-56)(36-63)(37-61)(38-54)(39-57)(40-59)(41-62)(42-68)(43-71)(44-70)(44-87)(45-72)(45-90)(46-51)(46-88)(47-55)(47-85)(48-50)(48-53)(49-50)(49-67)(51-60)(52-60)(52-70)(53-78)(54-61)(54-64)(55-73)(56-59)(56-80)(57-59)(57-62)(58-68)(58-79)(61-89)(62-69)(63-71)(63-81)(64-65)(65-72)(66-74)(66-84)(67-71)(67-78)(68-69)(69-80)(70-88)(72-89)(73-94)(74-91)(75-82)(75-91)(76-83)(76-91)(77-85)(77-86)(77-94)(78-92)(79-87)(79-93)(80-93)(81-90)(81-92)(82-97)(83-97)(84-98)(85-98)(86-95)(86-96)(87-99)(88-99)(89-100)(90-100)(92-101)(93-101)(94-101)(99-101)(100-101)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 1e+02 | 0.64 | 10.1002/advs.202407236 | 2024 |
🧬 Cell Death Types (1)
Apoptosis
high
«Ultimately, the inhibition of autophagy resulted in apoptotic cell death as analyzed by flow cytometry using Annexin V‐Alexa Fluor 488 and propidium iodide.»