Info
| ID | 579 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | Ru6 |
| SMILES | Cc1cc(C)c(/N=C/c2ccccc2N)c(C)c1.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C26ClN2Ru/(1-23)(2-20)(3-21)(4-18)(5-18)(6-19)(7-8)(7-19)(8-17)(9-16)(9-17)(10-11)(10-12)(11-25)(12-15)(13-20)(13-23)(14-21)(14-23)(15-22)(16-19)(17-18)(20-26)(21-26)(22-24)(22-25)(24-28)(25-27)(26-28)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 6.5 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| HeLa | 6.6 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| A549cisR | 8.2 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| HepG2 | 11 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| BEAS-2B | 22 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«Further, the induction of cell apoptosis and the perturbation of the cell cycle in the G0/G1 phase were also observed for these complexes.»