Info
| ID | 5733 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 3} |
| Abbreviation | Ir2N3 |
| SMILES | CC1(C)COC(c2[c-]cc(C[N-][N+]#N)cc2)=N1.[Cl-].c1cc[cH-]c1 |
TUCAN
C17H18IrN4O/(1-19)(2-19)(3-22)(4-19)(5-32)(6-27)(7-23)(8-24)(9-25)(10-32)(11-28)(12-26)(13-20)(14-29)(15-34)(16-20)(17-20)(18-34)(19-33)(20-33)(21-29)(21-31)(22-23)(22-24)(23-25)(24-26)(25-26)(27-28)(27-31)(28-30)(29-30)(30-32)(31-35)(32-38)(33-34)(33-36)(34-40)(35-36)(35-40)(37-39)(38-39)(38-41)(39-41)(40-41)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A2780cisR | 3.2 | — | 10.1021/acs.jmedchem.3c02000 | 2024 |
| A2780 | 3.9 | — | 10.1021/acs.jmedchem.3c02000 | 2024 |
| HuH-7 | 5.3 | — | 10.1021/acs.jmedchem.3c02000 | 2024 |
| HEK293 | 5.5 | — | 10.1021/acs.jmedchem.3c02000 | 2024 |
| HeLa | 5.8 | — | 10.1021/acs.jmedchem.3c02000 | 2024 |