Info
| ID | 5692 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 3} |
| Abbreviation | 3 |
| SMILES | COC(=O)c1cc(N=Cc2ncc[nH]2)ccc1O.Cc1c(C)c(C)[c-](C)c1C.[Cl-] |
TUCAN
C22H26IrN3O3/(1-27)(2-27)(3-27)(4-28)(5-28)(6-28)(7-29)(8-29)(9-29)(10-30)(11-30)(12-30)(13-31)(14-31)(15-31)(16-42)(17-43)(18-34)(19-46)(20-46)(21-46)(22-41)(23-32)(24-33)(25-49)(26-53)(27-35)(28-36)(29-37)(30-38)(31-39)(32-33)(32-47)(33-44)(34-40)(34-44)(35-36)(35-37)(36-38)(37-39)(38-39)(40-47)(40-48)(41-42)(41-49)(42-50)(43-45)(43-51)(44-51)(45-49)(45-50)(46-54)(47-53)(48-52)(48-54)(50-55)(51-55)(54-55)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HepG2 | 3.5 | — | 10.1021/acs.jmedchem.3c01092 | 2023 |
| MIA PaCa-2 | 3.7 | — | 10.1021/acs.jmedchem.3c01092 | 2023 |
| MDA-MB-231 | 4.5 | — | 10.1021/acs.jmedchem.3c01092 | 2023 |
| HT-29 | 4.8 | — | 10.1021/acs.jmedchem.3c01092 | 2023 |