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Complex #5689 — Ir(3) [Ir2]

2D Structure

Structure
⬇ MOL V3000

Info

ID5689
MetalIr
Oxidation state3
Charge1
Donor atoms{"N": 4}
AbbreviationIr2
SMILESCCCCOc1ccc(-c2nc3c4cccnc4c4ncccc4c3[nH]2)cc1.Cc1c(C)c(C)[c-](C)c1C.[Cl-]

TUCAN

C33H35IrN4O/(1-67)(2-36)(3-36)(4-36)(5-45)(6-37)(7-37)(8-37)(9-39)(10-60)(11-43)(12-39)(13-39)(14-40)(15-40)(16-40)(17-41)(18-61)(19-41)(20-41)(21-44)(22-42)(23-38)(24-38)(25-50)(26-51)(27-51)(28-38)(29-50)(30-46)(31-49)(32-47)(33-48)(34-67)(35-70)(36-52)(37-53)(38-51)(39-54)(40-56)(41-57)(42-43)(42-68)(43-59)(44-45)(44-60)(45-55)(46-47)(46-61)(47-58)(48-49)(48-59)(49-68)(50-51)(50-67)(52-53)(52-54)(53-56)(54-57)(55-62)(55-63)(56-57)(58-64)(58-65)(59-66)(60-69)(61-71)(62-64)(62-69)(63-65)(63-70)(64-71)(65-72)(66-70)(66-72)(67-73)(68-73)(71-74)(72-74)(73-74)

Measurements (3)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
HeLa28 10.1021/acs.inorgchem.4c03975 2024
A54946 10.1021/acs.inorgchem.4c03975 2024
BEAS-2B51 10.1021/acs.inorgchem.4c03975 2024

🧬 Cell Death Types (1)

Apoptosis high
«thereby leading to intrinsic apoptotic pathways»