Info
| ID | 5638 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | Ir2 |
| SMILES | Cc1c(C)c(C)[c-](C)c1C.Cc1cc(C)c(/N=C/c2ccccc2[NH-])c(C)c1 |
TUCAN
C26H32IrN2/(1-42)(2-56)(3-37)(4-37)(5-37)(6-33)(7-33)(8-33)(9-34)(10-34)(11-34)(12-35)(13-35)(14-45)(15-39)(16-43)(17-40)(18-46)(19-41)(20-39)(21-40)(22-40)(23-44)(24-39)(25-35)(26-36)(27-36)(28-36)(29-38)(30-38)(31-38)(32-59)(33-48)(34-49)(35-50)(36-52)(37-51)(38-53)(39-55)(40-54)(41-43)(41-57)(42-44)(42-47)(43-44)(45-51)(45-55)(46-54)(46-55)(47-56)(47-57)(48-49)(48-50)(49-52)(50-53)(51-58)(52-53)(54-58)(56-60)(57-59)(58-60)(59-61)(60-61)
Measurements (10)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 8.3 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| HeLa | 8.8 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| A549cisR | 10 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| HeLa | 10 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| A549 | 11 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| HepG2 | 12 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| A549cisR | 13 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| HepG2 | 15 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| BEAS-2B | 22 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
| BEAS-2B | 23 | — | 10.1021/acs.inorgchem.3c03471 | 2023 |
🧬 Cell Death Types (1)
Apoptosis
high
«Further, the induction of cell apoptosis and the perturbation of the cell cycle in the G0/G1 phase were also observed for these complexes.»