Info
| ID | 5607 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | 2b |
| SMILES | Cc1ccnc(-c2cc(CO)ccn2)c1.Fc1c[c-]c(-c2ccccn2)c(F)c1.Fc1c[c-]c(-c2ccccn2)c(F)c1 |
TUCAN
C34H24F4IrN4O/(1-33)(2-39)(3-29)(4-40)(5-41)(6-49)(7-54)(8-54)(9-32)(10-30)(11-37)(12-34)(13-28)(14-36)(15-31)(16-25)(17-35)(18-47)(19-38)(20-46)(21-48)(22-25)(23-25)(24-63)(25-44)(26-39)(26-42)(27-41)(27-43)(28-55)(28-56)(29-35)(29-50)(30-35)(30-46)(31-44)(31-49)(32-45)(32-52)(33-45)(33-47)(34-38)(34-48)(36-57)(36-58)(37-44)(37-53)(38-40)(39-55)(40-51)(41-57)(42-50)(42-56)(43-51)(43-58)(45-54)(46-59)(47-62)(48-61)(49-60)(50-59)(51-61)(52-53)(52-62)(53-60)(54-63)(55-64)(56-65)(57-66)(58-67)(59-68)(60-68)(61-68)(62-68)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 1.5 | — | 10.1002/chem.201703157 | 2017 |
| HepG2 | 2.2 | — | 10.1002/chem.201703157 | 2017 |
| A549cisR | 5.6 | — | 10.1002/chem.201703157 | 2017 |
| A549 | 10 | — | 10.1002/chem.201703157 | 2017 |
| LO2 | 13 | — | 10.1002/chem.201703157 | 2017 |
🧬 Cell Death Types (1)
Apoptosis
high
«cell death induced by 1a-3a mainly occurs through the caspase-dependent apoptotic pathway»
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
Loading source metadata…
The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.