Info
| ID | 5557 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 6} |
| Abbreviation | OnIr4 |
| SMILES | [c-]1ccccc1-c1nc2ccccc2s1.[c-]1ccccc1-c1nc2ccccc2s1.c1ccc2sc(-c3ccnc(-c4cc(-c5nc6ccccc6s5)ccn4)c3)nc2c1 |
TUCAN
C50H30IrN6S4/(1-36)(2-52)(3-41)(4-34)(5-37)(6-38)(7-43)(8-55)(9-51)(10-39)(11-59)(12-50)(13-33)(14-58)(15-40)(16-54)(17-44)(18-53)(19-35)(20-56)(21-46)(22-57)(23-65)(24-66)(25-45)(26-49)(27-48)(28-42)(29-60)(30-47)(31-38)(31-62)(32-58)(32-64)(33-40)(33-43)(34-43)(34-73)(35-44)(35-55)(36-63)(36-66)(37-44)(37-68)(38-46)(39-41)(39-46)(40-67)(41-62)(42-57)(42-69)(45-61)(45-72)(47-49)(47-64)(48-59)(48-74)(49-60)(50-63)(50-70)(51-52)(51-56)(52-76)(53-56)(53-71)(54-61)(54-65)(55-75)(57-59)(58-60)(61-77)(62-79)(63-78)(64-80)(65-81)(66-85)(67-73)(67-84)(68-75)(68-82)(69-74)(69-86)(70-72)(70-85)(71-76)(71-83)(72-81)(73-89)(74-90)(75-88)(76-87)(77-83)(77-87)(78-82)(78-88)(79-84)(79-89)(80-86)(80-90)(83-91)(84-91)(85-91)(86-91)(89-91)(90-91)
Measurements (23)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549cisR | 0.82 | — | 10.1039/C8SC01142G | 2018 |
| MCF-7 | 1.4 | — | 10.1039/C8SC01142G | 2018 |
| MCF-7/DOX | 1.5 | — | 10.1039/C8SC01142G | 2018 |
| HeLa | 1.6 | — | 10.1039/C8SC01142G | 2018 |
| KCP4 | 1.6 | — | 10.1039/C8SC01142G | 2018 |
| KB-C2 | 1.7 | — | 10.1039/C8SC01142G | 2018 |
| HCT-116 | 1.9 | — | 10.1039/C8SC01142G | 2018 |
| BEL-7404 | 2 | — | 10.1039/C8SC01142G | 2018 |
| BEL-7402 | 2 | — | 10.1039/C8SC01142G | 2018 |
| H460/MX20 | 2 | — | 10.1039/C8SC01142G | 2018 |
| KB-3-1 | 2 | — | 10.1039/C8SC01142G | 2018 |
| BEL-7404R | 2.1 | — | 10.1039/C8SC01142G | 2018 |
| NCI-H460 | 2.1 | — | 10.1039/C8SC01142G | 2018 |
| KB-CV60 | 2.2 | — | 10.1039/C8SC01142G | 2018 |
| KB/ATO | 2.2 | — | 10.1039/C8SC01142G | 2018 |
| A549 | 2.4 | — | 10.1039/C8SC01142G | 2018 |
| SK-OV-3 | 2.9 | — | 10.1039/C8SC01142G | 2018 |
| SW620/AD300 | 3.2 | — | 10.1039/C8SC01142G | 2018 |
| SKOV/Pt | 3.2 | — | 10.1039/C8SC01142G | 2018 |
| SW620 | 3.2 | — | 10.1039/C8SC01142G | 2018 |
| HEK293 | 4.1 | — | 10.1039/C8SC01142G | 2018 |
| HepG2 | 4.4 | — | 10.1039/C8SC01142G | 2018 |
| HL-7702 | 16 | — | 10.1039/C8SC01142G | 2018 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.