Info
| ID | 5465 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | 2 |
| SMILES | CCn1[c-][n+](Cn2[c-][n+](CC)cc2)cc1.[c-]1ccccc1-c1ccccn1.[c-]1ccccc1-c1ccccn1 |
TUCAN
C33H32IrN6/(1-43)(2-40)(3-38)(4-37)(5-39)(6-42)(7-56)(8-58)(9-55)(10-57)(11-33)(12-65)(13-59)(14-59)(15-65)(16-47)(17-49)(18-41)(19-48)(20-53)(21-33)(22-60)(23-33)(24-34)(25-44)(26-54)(27-46)(28-45)(29-50)(30-60)(31-34)(32-34)(33-59)(34-60)(35-40)(35-51)(36-41)(36-52)(37-40)(37-42)(38-39)(38-49)(39-61)(41-44)(42-43)(43-51)(44-47)(45-47)(45-52)(46-48)(46-50)(48-62)(49-53)(50-54)(51-61)(52-62)(53-70)(54-71)(55-56)(55-67)(56-66)(57-58)(57-69)(58-68)(59-67)(60-69)(61-70)(62-71)(63-66)(63-67)(64-68)(64-69)(65-66)(65-68)(70-72)(71-72)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 1.2 | 0.13 | 10.1016/j.biomaterials.2014.10... | 2015 |
| A549 | 3.4 | 0.098 | 10.1016/j.biomaterials.2014.10... | 2015 |
| A549cisR | 3.8 | 0.0028 | 10.1016/j.biomaterials.2014.10... | 2015 |
| MCF-7 | 6 | — | 10.1016/j.biomaterials.2014.10... | 2015 |
| HepG2 | 6.2 | — | 10.1016/j.biomaterials.2014.10... | 2015 |
| LO2 | 11 | — | 10.1016/j.biomaterials.2014.10... | 2015 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.