Info
| ID | 5464 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | 1 |
| SMILES | C[n+]1[c-]n(Cn2[c-][n+](C)cc2)cc1.[c-]1ccccc1-c1ccccn1.[c-]1ccccc1-c1ccccn1 |
TUCAN
C31H28IrN6/(1-34)(2-32)(3-38)(4-31)(5-41)(6-33)(7-47)(8-47)(9-59)(10-59)(11-47)(12-48)(13-48)(14-52)(15-54)(16-51)(17-40)(18-42)(19-36)(20-44)(21-49)(22-48)(23-35)(24-50)(25-39)(26-37)(27-43)(28-53)(29-32)(29-45)(30-36)(30-46)(31-32)(31-33)(33-34)(34-45)(35-36)(35-40)(37-40)(37-46)(38-41)(38-42)(39-43)(39-44)(41-55)(42-49)(43-50)(44-56)(45-55)(46-56)(47-60)(48-63)(49-64)(50-65)(51-52)(51-60)(52-61)(53-54)(53-63)(54-62)(55-64)(56-65)(57-60)(57-61)(58-62)(58-63)(59-61)(59-62)(64-66)(65-66)
Measurements (7)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 1.5 | 0.15 | 10.1016/j.biomaterials.2014.10... | 2015 |
| A549cisR | 5.3 | 0.019 | 10.1016/j.biomaterials.2014.10... | 2015 |
| A549 | 5.7 | 0.16 | 10.1016/j.biomaterials.2014.10... | 2015 |
| HepG2 | 9.8 | — | 10.1016/j.biomaterials.2014.10... | 2015 |
| MCF-7 | 10 | — | 10.1016/j.biomaterials.2014.10... | 2015 |
| HeLa | 14 | — | 10.1039/C5SC04458H | 2016 |
| LO2 | 17 | — | 10.1016/j.biomaterials.2014.10... | 2015 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.