Info
| ID | 5446 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 1, "P": 1} |
| Abbreviation | Ir8 |
| SMILES | C(=N/CCc1ccccc1)\c1ccccc1P(c1ccccc1)c1ccccc1.Cc1c(C)c(C)[c-](-c2ccc(-c3ccccc3)cc2)c1C.[Cl-] |
TUCAN
C48H45IrNP/(1-63)(2-47)(3-65)(4-46)(5-46)(6-53)(7-66)(8-46)(9-47)(10-47)(11-50)(12-49)(13-58)(14-49)(15-51)(16-57)(17-60)(18-61)(19-59)(20-73)(21-54)(22-68)(23-76)(24-77)(25-69)(26-70)(27-71)(28-72)(29-52)(30-48)(31-55)(32-62)(33-74)(34-64)(35-48)(36-48)(37-49)(38-56)(39-67)(40-75)(41-78)(42-90)(43-89)(44-90)(45-78)(46-80)(47-82)(48-85)(49-86)(50-51)(50-83)(51-81)(52-62)(52-83)(53-55)(53-58)(54-73)(54-76)(55-57)(56-61)(56-72)(57-59)(58-91)(59-91)(60-73)(60-92)(61-74)(62-81)(63-65)(63-66)(64-66)(64-67)(65-79)(67-79)(68-69)(68-87)(69-70)(70-71)(71-77)(72-75)(74-93)(75-93)(76-88)(77-87)(78-87)(78-90)(79-81)(80-82)(80-86)(82-84)(83-84)(84-85)(85-86)(88-89)(88-92)(89-94)(90-94)(91-95)(92-95)(93-95)(94-96)(95-96)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 4.7 | — | 10.1021/acs.organomet.9b00080 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«From abstract: 'this family of complexes causes cell death by cell stress, inducing apoptosis and necrosis'»