Info
| ID | 5445 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 1, "P": 1} |
| Abbreviation | Ir7 |
| SMILES | C(=N/C1CCCCC1)\c1ccccc1P(c1ccccc1)c1ccccc1.Cc1c(C)c(C)[c-](-c2ccc(-c3ccccc3)cc2)c1C.[Cl-] |
TUCAN
C46H47IrNP/(1-52)(2-49)(3-56)(4-48)(5-48)(6-48)(7-50)(8-50)(9-62)(10-49)(11-49)(12-53)(13-55)(14-58)(15-61)(16-57)(17-60)(18-59)(19-73)(20-74)(21-76)(22-76)(23-77)(24-77)(25-69)(26-72)(27-78)(28-75)(29-75)(30-79)(31-79)(32-78)(33-66)(34-54)(35-51)(36-68)(37-64)(38-70)(39-65)(40-51)(41-51)(42-50)(43-71)(44-63)(45-67)(46-90)(47-89)(48-85)(49-80)(50-86)(51-83)(52-56)(52-62)(53-55)(53-81)(54-64)(54-81)(55-84)(56-87)(57-58)(57-61)(58-91)(59-60)(59-91)(60-61)(62-65)(63-65)(63-87)(64-84)(66-70)(66-93)(67-70)(67-71)(68-71)(68-93)(69-72)(69-92)(72-73)(73-74)(74-88)(75-76)(75-79)(76-77)(77-90)(78-79)(78-90)(80-82)(80-85)(81-82)(82-83)(83-86)(84-87)(85-86)(88-89)(88-92)(89-94)(90-94)(91-95)(92-95)(93-95)(94-96)(95-96)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 5.8 | — | 10.1021/acs.organomet.9b00080 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«From abstract: 'this family of complexes causes cell death by cell stress, inducing apoptosis and necrosis'»