Info
| ID | 5444 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 1, "P": 1} |
| Abbreviation | Ir6 |
| SMILES | C(=N/CCc1ccccc1)\c1ccccc1P(c1ccccc1)c1ccccc1.Cc1c(C)c(C)[c-](C)c1C.[Cl-] |
TUCAN
C37H39IrNP/(1-40)(2-40)(3-40)(4-41)(5-41)(6-47)(7-45)(8-49)(9-41)(10-46)(11-42)(12-42)(13-42)(14-51)(15-52)(16-43)(17-54)(18-48)(19-50)(20-62)(21-59)(22-61)(23-63)(24-60)(25-64)(26-64)(27-73)(28-73)(29-72)(30-53)(31-43)(32-43)(33-57)(34-44)(35-55)(36-44)(37-56)(38-44)(39-58)(40-65)(41-66)(42-67)(43-68)(44-69)(45-47)(45-48)(46-48)(46-49)(47-75)(49-75)(50-51)(50-54)(51-52)(52-76)(53-54)(53-76)(55-56)(55-74)(56-57)(57-58)(58-70)(59-61)(59-71)(60-63)(60-71)(61-62)(62-63)(64-71)(64-73)(65-66)(65-67)(66-68)(67-69)(68-69)(70-72)(70-74)(72-77)(73-77)(74-78)(75-78)(76-78)(77-79)(78-79)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 7.9 | — | 10.1021/acs.organomet.9b00080 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«From abstract: 'this family of complexes causes cell death by cell stress, inducing apoptosis and necrosis'»