Info
| ID | 5443 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 1, "P": 1} |
| Abbreviation | Ir5 |
| SMILES | C(=N/Cc1ccccc1)\c1ccccc1P(c1ccccc1)c1ccccc1.Cc1c(C)c(C)[c-](C)c1C.[Cl-] |
TUCAN
C36H37IrNP/(1-38)(2-38)(3-38)(4-39)(5-45)(6-44)(7-43)(8-39)(9-48)(10-39)(11-40)(12-40)(13-40)(14-50)(15-41)(16-51)(17-46)(18-47)(19-57)(20-56)(21-58)(22-69)(23-61)(24-60)(25-59)(26-70)(27-70)(28-49)(29-41)(30-41)(31-54)(32-42)(33-52)(34-42)(35-53)(36-42)(37-55)(38-62)(39-63)(40-64)(41-65)(42-66)(43-45)(43-71)(44-45)(44-46)(46-50)(47-48)(47-51)(48-49)(49-52)(50-71)(51-72)(52-72)(53-54)(53-73)(54-55)(55-56)(56-67)(57-58)(57-61)(58-68)(59-60)(59-68)(60-61)(62-63)(62-64)(63-65)(64-66)(65-66)(67-69)(67-73)(68-70)(69-74)(70-74)(71-75)(72-75)(73-75)(74-76)(75-76)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 6.3 | — | 10.1021/acs.organomet.9b00080 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«From abstract: 'this family of complexes causes cell death by cell stress, inducing apoptosis and necrosis'»