Info
| ID | 5442 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 1, "P": 1} |
| Abbreviation | Ir4 |
| SMILES | C(=N/C1CCCCC1)\c1ccccc1P(c1ccccc1)c1ccccc1.Cc1c(C)c(C)[c-](C)c1C.[Cl-] |
TUCAN
C35H41IrNP/(1-42)(2-42)(3-42)(4-43)(5-43)(6-43)(7-49)(8-44)(9-44)(10-44)(11-50)(12-51)(13-47)(14-45)(15-55)(16-48)(17-53)(18-60)(19-59)(20-63)(21-63)(22-61)(23-61)(24-64)(25-64)(26-62)(27-62)(28-65)(29-65)(30-73)(31-72)(32-56)(33-45)(34-45)(35-57)(36-46)(37-54)(38-46)(39-52)(40-46)(41-58)(42-66)(43-67)(44-68)(45-69)(46-70)(47-49)(47-55)(48-50)(48-55)(49-74)(50-74)(51-53)(51-75)(52-54)(52-75)(53-56)(54-56)(57-58)(57-76)(58-59)(59-60)(60-71)(61-62)(61-65)(62-63)(63-73)(64-65)(64-73)(66-67)(66-68)(67-69)(68-70)(69-70)(71-72)(71-76)(72-77)(73-77)(74-78)(75-78)(76-78)(77-79)(78-79)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 25 | — | 10.1021/acs.organomet.9b00080 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«From abstract: 'this family of complexes causes cell death by cell stress, inducing apoptosis and necrosis'»