Info
| ID | 5440 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 1, "P": 1} |
| Abbreviation | Ir2 |
| SMILES | Cc1c(C)c(C)[c-](C)c1C.Cc1cccc(C)c1/N=C/c1ccccc1P(c1ccccc1)c1ccccc1.[Cl-] |
TUCAN
C37H39IrNP/(1-48)(2-58)(3-61)(4-72)(5-60)(6-40)(7-40)(8-40)(9-41)(10-41)(11-51)(12-45)(13-45)(14-47)(15-50)(16-54)(17-56)(18-49)(19-59)(20-45)(21-46)(22-55)(23-52)(24-57)(25-46)(26-46)(27-53)(28-63)(29-62)(30-41)(31-42)(32-42)(33-42)(34-43)(35-43)(36-43)(37-44)(38-44)(39-44)(40-64)(41-65)(42-66)(43-67)(44-68)(45-69)(46-71)(47-51)(47-75)(48-58)(48-74)(49-51)(49-54)(50-54)(50-75)(52-56)(52-76)(53-57)(53-76)(55-56)(55-57)(58-60)(59-62)(59-69)(60-61)(61-70)(62-63)(63-71)(64-65)(64-66)(65-67)(66-68)(67-68)(69-73)(70-72)(70-74)(71-73)(72-77)(73-77)(74-78)(75-78)(76-78)(77-79)(78-79)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 7.2 | — | 10.1021/acs.organomet.9b00080 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«From abstract: 'this family of complexes causes cell death by cell stress, inducing apoptosis and necrosis'»