Info
| ID | 5439 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 1, "P": 1} |
| Abbreviation | Ir1 |
| SMILES | C(=N/c1ccccc1)\c1ccccc1P(c1ccccc1)c1ccccc1.Cc1c(C)c(C)[c-](C)c1C.[Cl-] |
TUCAN
C35H35IrNP/(1-36)(2-36)(3-36)(4-42)(5-45)(6-44)(7-37)(8-47)(9-37)(10-37)(11-38)(12-38)(13-38)(14-41)(15-39)(16-43)(17-49)(18-53)(19-57)(20-66)(21-54)(22-58)(23-56)(24-55)(25-59)(26-46)(27-39)(28-39)(29-51)(30-40)(31-48)(32-40)(33-50)(34-40)(35-52)(36-60)(37-61)(38-62)(39-63)(40-64)(41-42)(41-68)(42-44)(43-45)(43-68)(44-45)(46-47)(46-48)(47-49)(48-50)(49-69)(50-69)(51-52)(51-70)(52-53)(53-54)(54-65)(55-56)(55-59)(56-57)(57-67)(58-59)(58-67)(60-61)(60-62)(61-63)(62-64)(63-64)(65-66)(65-70)(66-71)(67-71)(68-72)(69-72)(70-72)(71-73)(72-73)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 6.5 | — | 10.1021/acs.organomet.9b00080 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«From abstract: 'this family of complexes causes cell death by cell stress, inducing apoptosis and necrosis'»