Info
| ID | 528 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1} |
| Abbreviation | 1a |
| SMILES | CC(C)=CCC1=C([O-])C(=O)c2ccccc2C1=O.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C25ClO3Ru/(1-20)(2-16)(3-18)(4-16)(5-20)(6-7)(6-21)(7-10)(8-9)(8-18)(9-17)(10-12)(11-14)(11-19)(12-22)(13-15)(13-17)(14-20)(15-18)(16-17)(19-23)(19-25)(21-22)(21-25)(22-24)(23-24)(23-28)(24-27)(25-26)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| CH-1 | 4.1 | — | 10.1039/C3CC40432C | 2013 |
| SW480 | 4.1 | — | 10.1039/C3CC40432C | 2013 |
| HCT-116 | 19 | — | 10.1039/C3CC40432C | 2013 |
| A549 | 20 | — | 10.1039/C3CC40432C | 2013 |
| HL60 | 25 | — | 10.1039/C3CC40432C | 2013 |
🧬 Cell Death Types (1)
Apoptosis
high
«The complexes induced moderate but significant levels of apoptosis as determined by means of the annexin V assay in SW480 cells.»