Info
| ID | 5243 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"O": 1, "N": 4} |
| Abbreviation | 1 |
| SMILES | O=[N+]([O-])c1cc2cccnc2c2ncccc12.[c-]1ccccc1-c1ccccn1.[c-]1ccccc1-c1ccccn1 |
TUCAN
C34H23IrN5O2/(1-49)(2-27)(3-39)(4-50)(5-33)(6-28)(7-34)(8-26)(9-41)(10-37)(11-44)(12-51)(13-30)(14-40)(15-29)(16-42)(17-43)(18-52)(19-31)(20-35)(21-32)(22-38)(23-36)(24-34)(24-45)(25-37)(25-47)(26-28)(26-39)(27-29)(27-34)(28-53)(29-33)(30-31)(30-51)(31-48)(32-37)(32-38)(33-45)(35-40)(35-41)(36-44)(36-52)(38-42)(39-49)(40-50)(41-56)(42-47)(43-46)(43-57)(44-46)(45-53)(46-54)(47-56)(48-55)(48-57)(49-59)(50-60)(51-62)(52-61)(53-59)(54-55)(54-61)(55-62)(56-60)(57-58)(58-63)(58-64)(59-65)(60-65)(61-65)(62-65)
Measurements (7)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| SGC-7901 | 3.6 | — | 10.3390/molecules24173129 | 2019 |
| A549 | 14 | — | 10.3390/molecules24173129 | 2019 |
| NIH-3T3 | 15 | — | 10.3390/molecules24173129 | 2019 |
| HeLa | 16 | — | 10.3390/molecules24173129 | 2019 |
| EC109 | 20 | — | 10.3390/molecules24173129 | 2019 |
| BEL-7402 | 23 | — | 10.3390/molecules24173129 | 2019 |
| HepG2 | 31 | — | 10.3390/molecules24173129 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«The results reveal that these complexes can indeed induce apoptosis, with 1 displaying the highest apoptotic effect.»