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Complex #5240 — Ir(3) [11]

2D Structure

Structure
⬇ MOL V3000

Info

ID5240
MetalIr
Oxidation state3
Charge1
Donor atoms{"N": 2}
Abbreviation11
SMILESCC(C)n1[c-][n+](/C(=N/c2ccccc2)c2ccccc2)cc1.Cc1c(C)c(C)[c-](C)c1C.[Cl-]

TUCAN

C29ClIrN3/(1-18)(2-19)(3-20)(4-21)(5-27)(6-27)(7-23)(8-16)(8-22)(9-10)(9-13)(10-11)(11-26)(12-13)(12-26)(14-17)(14-22)(15-16)(15-17)(18-19)(18-20)(19-21)(20-23)(21-23)(22-29)(24-25)(24-32)(25-31)(26-30)(27-32)(28-31)(28-32)(29-30)(29-31)

Measurements (1)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A549 10.1021/acs.inorgchem.8b01656 2018

🧬 Cell Death Types (1)

Apoptosis high
«When complexes 4 and 8 is at 3 equipotent concentrations of IC50, a total of 78.1% and 80.1% of cells were undergoing apoptosis, respectively.»