Info
| ID | 5239 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | 10 |
| SMILES | CCCCn1[c-][n+](/C(=N/c2c(C(C)C)cccc2C(C)C)c2ccccc2)cc1.Cc1c(C)c(C)[c-](C)c1C.[Cl-] |
TUCAN
C36ClIrN3/(1-22)(2-23)(3-24)(4-28)(5-21)(6-21)(7-27)(8-15)(9-27)(10-29)(11-15)(11-32)(12-13)(12-16)(13-25)(14-17)(14-30)(16-26)(17-18)(18-20)(19-20)(19-30)(21-25)(22-23)(22-24)(23-28)(24-29)(25-34)(26-27)(26-34)(28-29)(30-36)(31-33)(31-38)(32-39)(33-39)(34-37)(35-38)(35-39)(36-37)(36-38)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 3.6 | — | 10.1021/acs.inorgchem.8b01656 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«When complexes 4 and 8 is at 3 equipotent concentrations of IC50, a total of 78.1% and 80.1% of cells were undergoing apoptosis, respectively.»