Info
| ID | 5238 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | 9 |
| SMILES | CC(C)c1cccc(C(C)C)c1/N=C(\c1ccccc1)[n+]1[c-]n(C(C)C)cc1.Cc1c(C)c(C)[c-](C)c1C.[Cl-] |
TUCAN
C35ClIrN3/(1-20)(2-33)(3-20)(4-22)(5-26)(6-23)(7-24)(8-26)(9-25)(10-33)(11-27)(12-14)(12-21)(13-16)(13-21)(14-15)(15-16)(17-19)(17-28)(18-19)(18-29)(20-28)(21-35)(22-23)(22-24)(23-25)(24-27)(25-27)(26-29)(28-32)(29-32)(30-31)(30-38)(31-37)(32-36)(33-38)(34-37)(34-38)(35-36)(35-37)
Measurements (1)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 3.9 | — | 10.1021/acs.inorgchem.8b01656 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«When complexes 4 and 8 is at 3 equipotent concentrations of IC50, a total of 78.1% and 80.1% of cells were undergoing apoptosis, respectively.»