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Complex #5236 — Ir(3) [7]

2D Structure

Structure
⬇ MOL V3000

Info

ID5236
MetalIr
Oxidation state3
Charge1
Donor atoms{"N": 2}
Abbreviation7
SMILESC/C(=N\c1c(C(C)C)cccc1C(C)C)[n+]1[c-]n(C(C)C)cc1.Cc1c(C)c(C)[c-](C)c1C.[Cl-]

TUCAN

C30ClIrN3/(1-16)(2-19)(3-19)(4-30)(5-17)(6-20)(7-21)(8-24)(9-27)(10-27)(11-24)(12-22)(13-14)(13-18)(14-15)(15-23)(16-17)(16-20)(17-21)(18-19)(18-28)(20-22)(21-22)(23-24)(23-28)(25-26)(25-32)(26-33)(27-33)(28-31)(29-32)(29-33)(30-31)(30-32)

Measurements (1)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A5492.2 10.1021/acs.inorgchem.8b01656 2018

🧬 Cell Death Types (1)

Apoptosis high
«When complexes 4 and 8 is at 3 equipotent concentrations of IC50, a total of 78.1% and 80.1% of cells were undergoing apoptosis, respectively.»