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Complex #5231 — Ir(3) [2]

2D Structure

Structure
⬇ MOL V3000

Info

ID5231
MetalIr
Oxidation state3
Charge1
Donor atoms{"N": 2}
Abbreviation2
SMILESCCn1[c-][n+](/C(C)=N/c2c(C)cccc2C)cc1.Cc1c(C)c(C)[c-](C)c1C.[Cl-]

TUCAN

C25ClIrN3/(1-25)(2-13)(3-14)(4-15)(5-17)(6-16)(7-19)(8-22)(9-18)(10-11)(10-12)(11-16)(12-19)(13-14)(13-15)(14-17)(15-18)(16-23)(17-18)(19-23)(20-21)(20-28)(21-27)(22-28)(23-26)(24-27)(24-28)(25-26)(25-27)

Measurements (1)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A549 10.1021/acs.inorgchem.8b01656 2018

🧬 Cell Death Types (1)

Apoptosis high
«When complexes 4 and 8 is at 3 equipotent concentrations of IC50, a total of 78.1% and 80.1% of cells were undergoing apoptosis, respectively.»