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D-MPNN
Complex #5230 — Ir(3)
[1]
2D Structure
⬇ MOL V3000
Info
ID
5230
Metal
Ir
Oxidation state
3
Charge
1
Donor atoms
{"N": 2}
Abbreviation
1
SMILES
C/C(=N\c1c(C)cccc1C)[n+]1[c-]n(C)cc1.Cc1c(C)c(C)[c-](C)c1C.[Cl-]
TUCAN
C24ClIrN3/(1-12)(2-15)(3-13)(4-16)(5-17)(6-24)(7-14)(8-18)(9-10)(9-13)(10-11)(11-14)(12-15)(12-16)(13-22)(14-22)(15-17)(16-18)(17-18)(19-26)(20-21)(20-27)(21-26)(22-25)(23-26)(23-27)(24-25)(24-27)
Measurements (1)
Cell line
IC₅₀ dark (µM)
IC₅₀ light (µM)
DOI
Year
A549
—
—
10.1021/acs.inorgchem.8b01656
2018
🧬 Cell Death Types (1)
Apoptosis
high
«When complexes 4 and 8 is at 3 equipotent concentrations of IC50, a total of 78.1% and 80.1% of cells were undergoing apoptosis, respectively.»