Info
| ID | 5175 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 5} |
| Abbreviation | IrM2 |
| SMILES | Cn1c2ccccc2c2ccnc(-c3ccc4ccccc4n3)c21.[c-]1ccccc1-c1ccccn1.[c-]1ccccc1-c1ccccn1 |
TUCAN
C43H31IrN5/(1-34)(2-39)(3-36)(4-41)(5-44)(6-38)(7-45)(8-35)(9-37)(10-65)(11-53)(12-64)(13-64)(14-50)(15-64)(16-67)(17-48)(18-55)(19-46)(20-40)(21-42)(22-43)(23-54)(24-51)(25-49)(26-58)(27-47)(28-66)(29-56)(30-52)(31-57)(32-37)(32-62)(33-42)(33-63)(34-39)(34-62)(35-40)(35-41)(36-37)(36-39)(38-42)(38-44)(40-69)(41-65)(43-45)(43-52)(44-56)(45-66)(46-47)(46-74)(47-55)(48-49)(48-61)(49-70)(50-54)(50-60)(51-59)(51-67)(52-71)(53-57)(53-72)(54-57)(55-58)(56-63)(58-61)(59-60)(59-68)(60-72)(61-74)(62-69)(63-71)(64-75)(65-76)(66-79)(67-78)(68-73)(68-75)(69-76)(70-73)(70-77)(71-79)(72-75)(73-78)(74-77)(76-80)(77-80)(78-80)(79-80)
Measurements (6)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HeLa | 0.44 | — | 10.1039/C8DT00783G | 2018 |
| MCF-7 | 0.89 | — | 10.1039/C8DT00783G | 2018 |
| A549 | 0.93 | — | 10.1039/C8DT00783G | 2018 |
| A549cisR | 1 | — | 10.1039/C8DT00783G | 2018 |
| HepG2 | 1.1 | — | 10.1039/C8DT00783G | 2018 |
| LO2 | 4.9 | — | 10.1039/C8DT00783G | 2018 |
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
Loading source metadata…
The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.