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Complex #517 — Ru(2) [Ru1]

2D Structure

Structure
⬇ MOL V3000

Info

ID517
MetalRu
Oxidation state2
Charge2
Donor atoms{"N": 8}
AbbreviationRu1
SMILESClc1ccc(-c2ccc(-c3nc4c5cccnc5c5ncccc5c4[nH]3)cc2)cc1.c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1.c1ccc(-c2ccnc3c2ccc2c(-c4ccccc4)ccnc23)cc1

TUCAN

C73H47ClN8Ru/(1-48)(2-66)(3-49)(4-52)(5-67)(6-56)(7-106)(8-77)(9-50)(10-55)(11-57)(12-51)(13-107)(14-53)(15-78)(16-65)(17-62)(18-60)(19-72)(20-84)(21-73)(22-59)(23-58)(24-108)(25-109)(26-63)(27-64)(28-79)(29-69)(30-76)(31-80)(32-110)(33-105)(34-74)(35-81)(36-82)(37-54)(38-61)(39-71)(40-68)(41-83)(42-75)(43-86)(44-70)(45-85)(46-87)(47-122)(48-50)(48-52)(49-50)(49-56)(51-55)(51-57)(52-88)(53-55)(53-65)(54-71)(54-79)(56-88)(57-98)(58-62)(58-105)(59-60)(59-120)(60-103)(61-71)(61-80)(62-89)(63-90)(63-106)(64-92)(64-107)(65-98)(66-67)(66-91)(67-93)(68-75)(68-81)(69-94)(69-108)(70-74)(70-103)(72-73)(72-97)(73-102)(74-120)(75-83)(76-95)(76-109)(77-78)(77-96)(78-99)(79-100)(80-100)(81-101)(82-83)(82-101)(84-87)(84-97)(85-86)(85-104)(86-110)(87-102)(88-90)(89-116)(89-118)(90-91)(91-111)(92-93)(92-98)(93-112)(94-96)(94-100)(95-99)(95-101)(96-113)(97-119)(99-117)(102-103)(104-114)(104-115)(105-121)(106-123)(107-124)(108-127)(109-128)(110-125)(111-112)(111-123)(112-124)(113-117)(113-127)(114-118)(114-126)(115-116)(115-125)(116-121)(117-128)(118-122)(119-122)(119-126)(120-129)(123-130)(124-130)(125-130)(126-130)(127-130)(128-130)

Measurements (7)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A549—— 10.1016/j.ejmech.2023.115541 2023
HepG2—— 10.1016/j.ejmech.2023.115541 2023
SGC-7901—— 10.1016/j.ejmech.2023.115541 2023
LO2—— 10.1016/j.ejmech.2023.115541 2023
HeLa—— 10.1016/j.ejmech.2023.115541 2023
BEL-7402—— 10.1016/j.ejmech.2023.115541 2023
B16—— 10.1016/j.ejmech.2023.115541 2023