Info
| ID | 5057 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 0 |
| Donor atoms | {"N": 1} |
| Abbreviation | 2a |
| SMILES | Cc1c(C)c(C)[c-](C)c1C.[Cl-].[c-]1cccc2ccc3cccnc3c12 |
TUCAN
C23ClIrN/(1-15)(2-16)(3-18)(4-19)(5-20)(6-7)(6-21)(7-17)(8-9)(8-17)(9-10)(10-11)(11-14)(12-13)(12-22)(13-21)(14-17)(14-23)(15-16)(15-18)(16-19)(18-20)(19-20)(21-23)(22-24)(23-24)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 10 | 5.6 | 10.1021/acs.jmedchem.3c01276 | 2024 |
| MCF-7 | 15 | — | 10.1021/acs.jmedchem.9b02000 | 2020 |
| MRC-5 | 36 | — | 10.1021/acs.jmedchem.9b02000 | 2020 |
🧬 Cell Death Types (1)
Apoptosis
high
«Consequently, cell death by apoptosis and secondary necrosis is activated.»