Info
| ID | 4952 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 4} |
| Abbreviation | 4 |
| SMILES | [c-]1ccccc1-c1ccccn1.[c-]1ccccc1-c1ccccn1.c1ccc(C(=C(c2ccccc2)c2ccc(-c3ccnc(-c4cc(-c5ccc(C(=C(c6ccccc6)c6ccccc6)c6ccccc6)cc5)ccn4)c3)cc2)c2ccccc2)cc1 |
TUCAN
C84H60IrN4/(1-64)(2-63)(3-83)(4-137)(5-65)(6-138)(7-84)(8-74)(9-70)(10-81)(11-72)(12-75)(13-91)(14-85)(15-86)(16-71)(17-69)(18-88)(19-98)(20-115)(21-87)(22-90)(23-94)(24-73)(25-89)(26-95)(27-80)(28-92)(29-82)(30-96)(31-100)(32-97)(33-79)(34-109)(35-99)(36-104)(37-93)(38-117)(39-103)(40-116)(41-108)(42-101)(43-102)(44-118)(45-107)(46-76)(47-78)(48-67)(49-139)(50-77)(51-66)(52-111)(53-140)(54-110)(55-105)(56-114)(57-113)(58-68)(59-106)(60-112)(61-66)(61-120)(62-106)(62-135)(63-70)(63-121)(64-74)(64-75)(65-74)(65-122)(66-76)(67-76)(67-78)(68-77)(68-113)(69-75)(69-122)(70-123)(71-79)(71-109)(72-119)(72-137)(73-119)(73-141)(77-106)(78-120)(79-98)(80-85)(80-86)(81-92)(81-123)(82-88)(82-90)(83-85)(83-127)(84-86)(84-127)(87-88)(87-129)(89-90)(89-129)(91-124)(91-138)(92-121)(93-95)(93-100)(94-103)(94-126)(95-97)(96-116)(96-126)(97-131)(98-128)(99-100)(99-131)(101-124)(101-142)(102-104)(102-132)(103-133)(104-117)(105-107)(105-143)(107-110)(108-117)(108-118)(109-115)(110-139)(111-112)(111-114)(112-144)(113-135)(114-140)(115-128)(116-133)(118-132)(119-121)(120-143)(122-130)(123-130)(124-133)(125-127)(125-129)(125-130)(126-134)(128-134)(131-136)(132-136)(134-136)(135-144)(137-145)(138-147)(139-146)(140-148)(141-142)(141-145)(142-147)(143-146)(144-148)(145-149)(146-149)(147-149)(148-149)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | — | — | 10.1002/cbic.201900268 | 2019 |
| BEAS-2B | — | — | 10.1002/cbic.201900268 | 2019 |
| 16HBE | — | — | 10.1002/cbic.201900268 | 2019 |
🧬 Cell Death Types (1)
Apoptosis
high
«Complexes induce a dose-dependent increase in the percentage of apoptotic cells after 24 h of treatment. The percentage of early apoptosis and late apoptosis cells increased from 1.7% and 9.8% to 8.1%...»
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
Loading source metadata…
The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.