Info
| ID | 4938 |
| Metal | Ir |
| Oxidation state | 3 |
| Charge | 1 |
| Donor atoms | {"N": 2} |
| Abbreviation | Ir4 |
| SMILES | C/C(=N\c1c(C)cccc1C)[n+]1[c-]n(C)cc1.Cc1c(C)c(C)[c-](-c2ccc(-c3ccccc3)cc2)c1C.[Cl-] |
TUCAN
C35ClIrN3/(1-21)(2-27)(3-35)(4-23)(5-28)(6-22)(7-25)(8-12)(8-24)(9-13)(9-20)(10-12)(10-15)(11-16)(11-20)(13-29)(14-15)(14-24)(16-29)(17-19)(17-21)(18-19)(18-22)(20-24)(21-33)(22-33)(23-26)(23-27)(25-26)(25-28)(26-29)(27-28)(30-37)(31-32)(31-38)(32-37)(33-36)(34-37)(34-38)(35-36)(35-38)
Measurements (3)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| BEAS-2B | 3.4 | — | 10.1016/j.jinorgbio.2018.11.00... | 2019 |
| A549 | 4.4 | — | 10.1016/j.jinorgbio.2018.11.00... | 2019 |
| A549 | 7.4 | — | 10.1021/acs.inorgchem.8b01656 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
high
«When complexes 4 and 8 is at 3 equipotent concentrations of IC50, a total of 78.1% and 80.1% of cells were undergoing apoptosis, respectively.»