Info
| ID | 4819 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 6} |
| Abbreviation | RuCXB |
| SMILES | Cc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(=O)(=O)NCCCCCCOc3ccc(-c4nc5c6cccnc6c6ncccc6c5n4-c4ccccc4)cc3)cc2)cc1.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1 |
TUCAN
C68H56F3N11O3RuS/(1-71)(2-70)(3-91)(4-58)(5-74)(6-61)(7-101)(8-59)(9-62)(10-66)(11-121)(12-79)(13-102)(14-60)(15-64)(16-77)(17-73)(18-72)(19-76)(20-105)(21-63)(22-106)(23-104)(24-107)(25-67)(26-88)(27-65)(28-69)(29-82)(30-95)(31-86)(32-81)(33-107)(34-78)(35-68)(36-94)(37-92)(38-103)(39-80)(40-94)(41-87)(42-57)(43-92)(44-57)(45-75)(46-83)(47-90)(48-84)(49-57)(50-93)(51-93)(52-85)(53-89)(54-121)(55-95)(56-129)(57-96)(58-68)(58-97)(59-61)(59-101)(60-61)(60-108)(62-64)(62-66)(63-65)(63-88)(64-109)(65-110)(66-102)(67-69)(67-113)(68-122)(69-124)(70-81)(70-96)(71-72)(71-117)(72-77)(73-76)(73-117)(74-75)(74-103)(75-98)(76-77)(78-82)(78-113)(79-80)(79-100)(80-104)(81-99)(82-124)(83-90)(83-116)(84-85)(84-97)(85-122)(86-87)(86-96)(87-99)(88-105)(89-90)(89-106)(91-114)(91-118)(92-93)(92-94)(93-95)(94-121)(95-107)(97-120)(98-112)(98-115)(99-114)(100-111)(100-119)(101-130)(102-131)(103-125)(104-126)(105-133)(106-134)(107-129)(108-109)(108-130)(109-131)(110-116)(110-133)(111-112)(111-126)(112-125)(113-128)(114-128)(115-119)(115-132)(116-134)(117-127)(118-123)(118-135)(119-127)(120-127)(120-132)(121-136)(122-136)(123-139)(123-140)(123-141)(124-142)(128-135)(129-142)(130-143)(131-143)(132-143)(133-143)(134-143)(135-143)(137-142)(138-142)
Measurements (4)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| 4T1 | 29 | — | 10.1039/d4cc04217d | 2024 |
| HCT-116 | 30 | — | 10.1039/d4cc04217d | 2024 |
| MCF-7 | 36 | — | 10.1039/d4cc04217d | 2024 |
| HK-2 | 70 | — | 10.1039/d4cc04217d | 2024 |
🧬 Cell Death Types (2)
Apoptosis
high
«achieves a strong therapeutic effect through the synergistic induction of ferroptosis and apoptosis.»
Ferroptosis
high
«achieves a strong therapeutic effect through the synergistic induction of ferroptosis and apoptosis.»
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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