Info
| ID | 4815 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 8} |
| Abbreviation | Ru |
| SMILES | Oc1ccc(-c2nc3c4cccnc4c4ncccc4c3n2-c2ccccc2)cc1.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1 |
TUCAN
C45H32N8ORu/(1-61)(2-38)(3-37)(4-62)(5-34)(6-56)(7-63)(8-35)(9-33)(10-45)(11-57)(12-49)(13-39)(14-51)(15-44)(16-40)(17-42)(18-41)(19-43)(20-50)(21-36)(22-46)(23-66)(24-52)(25-64)(26-65)(27-55)(28-48)(29-47)(30-54)(31-53)(32-86)(33-37)(33-67)(34-37)(34-61)(35-47)(35-62)(36-46)(36-68)(38-40)(38-45)(39-44)(39-65)(40-56)(41-43)(41-60)(42-51)(42-77)(43-64)(44-58)(45-71)(46-49)(47-48)(48-72)(49-63)(50-53)(50-66)(51-59)(52-55)(52-77)(53-54)(54-73)(55-59)(56-57)(57-71)(58-69)(58-74)(59-76)(60-70)(60-75)(61-80)(62-81)(63-82)(64-78)(65-85)(66-83)(67-68)(67-80)(68-82)(69-75)(69-84)(70-74)(70-78)(71-79)(72-73)(72-81)(73-83)(74-85)(75-79)(76-79)(76-84)(77-86)(80-87)(81-87)(82-87)(83-87)(84-87)(85-87)(86-87)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| CT-26 | — | — | 10.1002/chem.202301742 | 2023 |
| MCF-7 | — | — | 10.1039/d4cc04217d | 2024 |
| 4T1 | — | — | 10.1039/d4cc04217d | 2024 |
| HCT-116 | — | — | 10.1039/d4cc04217d | 2024 |
| HK-2 | — | — | 10.1039/d4cc04217d | 2024 |
🧬 Cell Death Types (2)
Apoptosis
high
«achieves a strong therapeutic effect through the synergistic induction of ferroptosis and apoptosis.»
Ferroptosis
high
«achieves a strong therapeutic effect through the synergistic induction of ferroptosis and apoptosis.»
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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The generated SVG will appear here. The legacy ligand image above stays visible for side-by-side review.