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Complex #4755 — Ru(2) [1]

2D Structure

Structure
⬇ MOL V3000

Info

ID4755
MetalRu
Oxidation state2
Charge0
Donor atoms{"N": 2}
Abbreviation1
SMILESCc1ccc(C(C)C)cc1.Cc1ccc(NN)cc1C.[Cl-].[Cl-]

TUCAN

C18Cl2N2Ru/(1-15)(2-14)(3-14)(4-13)(5-17)(6-8)(6-16)(7-9)(7-13)(8-15)(9-18)(10-12)(10-15)(11-17)(11-18)(12-16)(13-17)(14-16)(18-20)(19-20)

Measurements (2)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
MDA-MB-23175 10.3390/biom15030350 2025
MIA PaCa-21e+02 10.3390/biom15030350 2025

🧬 Cell Death Types (1)

Apoptosis high
«The annexin V/PI apoptotic assay results showed that 1 and 2 exhibit different selectivity towards MIA PaCa-2 and MDA-MB-231 cancer cells.»