Info
| ID | 4755 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 2} |
| Abbreviation | 1 |
| SMILES | Cc1ccc(C(C)C)cc1.Cc1ccc(NN)cc1C.[Cl-].[Cl-] |
TUCAN
C18Cl2N2Ru/(1-15)(2-14)(3-14)(4-13)(5-17)(6-8)(6-16)(7-9)(7-13)(8-15)(9-18)(10-12)(10-15)(11-17)(11-18)(12-16)(13-17)(14-16)(18-20)(19-20)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| MDA-MB-231 | 75 | — | 10.3390/biom15030350 | 2025 |
| MIA PaCa-2 | 1e+02 | — | 10.3390/biom15030350 | 2025 |
🧬 Cell Death Types (1)
Apoptosis
high
«The annexin V/PI apoptotic assay results showed that 1 and 2 exhibit different selectivity towards MIA PaCa-2 and MDA-MB-231 cancer cells.»
Source-assisted 2D generator
Builds the drawing from source ligand graphs and explicit donor metadata, then uses Metal2D only for layout. Publication output uses black bonds without arrows or colour highlighting; validated octahedral enantiomers are encoded directly with solid and hashed wedge bonds.
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