Info
| ID | 4708 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 6} |
| Abbreviation | 2b |
| SMILES | c1ccc(-c2cccc(-c3cccc(-c4ccccn4)n3)n2)nc1.c1ccncc1.c1ccncc1 |
TUCAN
C30H24N6Ru/(1-39)(2-31)(3-48)(4-27)(5-47)(6-30)(7-42)(8-34)(9-35)(10-43)(11-44)(12-28)(13-25)(14-38)(15-33)(16-45)(17-46)(18-29)(19-36)(20-41)(21-32)(22-26)(23-40)(24-37)(25-27)(25-28)(26-29)(26-40)(27-43)(28-44)(29-45)(30-34)(30-42)(31-38)(31-52)(32-37)(32-49)(33-35)(33-36)(34-50)(35-48)(36-51)(37-39)(38-41)(39-53)(40-46)(41-47)(42-54)(43-57)(44-57)(45-58)(46-58)(47-55)(48-60)(49-51)(49-59)(50-52)(50-56)(51-60)(52-55)(53-54)(53-59)(54-56)(57-61)(58-61)(59-61)(60-61)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 93 | — | 10.1039/c6cc04813g | 2016 |
| HL60 | — | — | 10.1039/c6cc04813g | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«Furthermore, flow cytometry confirmed the mechanism of cell death for 2a occurs via apoptosis with no visible sign of necrosis.»