Info
| ID | 4707 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 4} |
| Abbreviation | 2a |
| SMILES | [Cl-].[Cl-].c1ccc(-c2cccc(-c3cccc(-c4ccccn4)n3)n2)nc1 |
TUCAN
C20H14N4Ru/(1-19)(2-20)(3-22)(4-26)(5-18)(6-24)(7-17)(8-23)(9-25)(10-27)(11-28)(12-16)(13-15)(14-21)(15-16)(15-17)(16-27)(17-29)(18-24)(18-28)(19-20)(19-25)(20-31)(21-24)(21-32)(22-23)(22-33)(23-26)(25-30)(26-34)(27-38)(28-36)(29-34)(29-38)(30-32)(30-35)(31-33)(31-35)(32-36)(33-37)(34-37)(37-39)(38-39)
Measurements (2)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| HL60 | 10 | — | 10.1039/c6cc04813g | 2016 |
| A549 | 10 | — | 10.1039/c6cc04813g | 2016 |
🧬 Cell Death Types (1)
Apoptosis
high
«Furthermore, flow cytometry confirmed the mechanism of cell death for 2a occurs via apoptosis with no visible sign of necrosis.»