Info
| ID | 47 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"O": 1, "N": 1} |
| Abbreviation | 2a |
| SMILES | [Cl-].[O-]c1ccc2ccccc2c1C=NCC1CCCCC1.c1ccccc1 |
TUCAN
C24ClNORu/(1-2)(1-3)(2-4)(3-10)(4-11)(5-8)(5-18)(6-7)(6-21)(7-15)(8-13)(9-12)(9-13)(10-11)(12-18)(14-15)(14-20)(16-17)(16-21)(17-24)(18-23)(19-20)(19-22)(19-24)(20-21)(22-25)(23-25)(24-26)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| T47D | 21 | — | 10.1021/acs.inorgchem.8b00346 | 2018 |
| A2780 | 30 | — | 10.1021/acs.inorgchem.8b00346 | 2018 |
| MCF-12A | 38 | — | 10.1021/acs.inorgchem.8b00346 | 2018 |
| SH-SY5Y | 67 | — | 10.1021/acs.inorgchem.8b00346 | 2018 |
| MCF-7 | 89 | — | 10.1021/acs.inorgchem.8b00346 | 2018 |
🧬 Cell Death Types (1)
Apoptosis
low
«The article does not explicitly state that complex 5a (ID 47) induces apoptosis. However, the MTS assay measures metabolic activity, which is a general cytotoxicity assay, not a specific cell death me...»