Info
| ID | 4674 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 7} |
| Abbreviation | 5 |
| SMILES | COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCn1ccnc1.Cc1ccc(C(C)C)cc1.NCCN |
TUCAN
C33H41ClFN7O2Ru/(1-42)(2-61)(3-42)(4-58)(5-61)(6-42)(7-62)(8-44)(9-46)(10-66)(11-45)(12-50)(13-62)(14-44)(15-47)(16-43)(17-44)(18-52)(19-69)(20-69)(21-69)(22-70)(23-67)(24-70)(25-63)(26-59)(27-54)(28-54)(29-60)(30-63)(31-43)(32-43)(33-49)(34-48)(35-51)(36-53)(37-75)(38-75)(39-76)(40-76)(41-78)(42-58)(43-55)(44-58)(45-46)(45-55)(46-56)(47-50)(47-55)(48-64)(48-74)(49-57)(49-72)(50-56)(51-53)(51-73)(52-65)(52-71)(53-64)(54-63)(54-70)(56-58)(57-65)(57-68)(59-60)(59-77)(60-79)(61-62)(61-75)(62-76)(63-79)(64-78)(65-81)(66-77)(66-79)(67-80)(67-81)(68-78)(68-80)(69-83)(70-82)(71-72)(71-83)(72-82)(73-74)(73-84)(74-85)(80-86)(81-86)(82-86)(83-86)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A431 | 29 | — | 10.1039/c5mt00122f | 2015 |
| A549 | 34 | — | 10.1039/c5mt00122f | 2015 |
| HeLa | 48 | — | 10.1039/c5mt00122f | 2015 |
| MCF-7 | 77 | — | 10.1039/c5mt00122f | 2015 |
| PC-3 | — | — | 10.1039/c5mt00122f | 2015 |
🧬 Cell Death Types (1)
Apoptosis
high
«complex 3 induced a large ratio of A549 cells early-stage apoptosis (56.8%)»