Info
| ID | 4673 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 2 |
| Donor atoms | {"N": 7} |
| Abbreviation | 4 |
| SMILES | COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCn1ccnc1.Cc1ccc(C(C)C)cc1.NCCN |
TUCAN
C32H39ClFN7O2Ru/(1-41)(2-58)(3-41)(4-55)(5-58)(6-41)(7-59)(8-42)(9-44)(10-43)(11-48)(12-59)(13-42)(14-45)(15-40)(16-42)(17-66)(18-66)(19-66)(20-47)(21-64)(22-50)(23-67)(24-57)(25-63)(26-60)(27-67)(28-56)(29-60)(30-40)(31-40)(32-46)(33-49)(34-51)(35-72)(36-72)(37-73)(38-73)(39-75)(40-53)(41-55)(42-55)(43-44)(43-53)(44-52)(45-48)(45-53)(46-61)(46-71)(47-54)(47-68)(48-52)(49-51)(49-70)(50-62)(50-69)(51-61)(52-55)(54-62)(54-65)(56-57)(56-74)(57-76)(58-59)(58-72)(59-73)(60-67)(60-76)(61-75)(62-78)(63-74)(63-76)(64-77)(64-78)(65-75)(65-77)(66-79)(67-80)(68-69)(68-80)(69-79)(70-71)(70-81)(71-82)(77-83)(78-83)(79-83)(80-83)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 24 | — | 10.1039/c5mt00122f | 2015 |
| A431 | 31 | — | 10.1039/c5mt00122f | 2015 |
| MCF-7 | 73 | — | 10.1039/c5mt00122f | 2015 |
| PC-3 | 78 | — | 10.1039/c5mt00122f | 2015 |
| HeLa | — | — | 10.1039/c5mt00122f | 2015 |
🧬 Cell Death Types (1)
Apoptosis
high
«complex 3 induced a large ratio of A549 cells early-stage apoptosis (56.8%)»