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Complex #4673 — Ru(2) [4]

2D Structure

Structure
⬇ MOL V3000

Info

ID4673
MetalRu
Oxidation state2
Charge2
Donor atoms{"N": 7}
Abbreviation4
SMILESCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCn1ccnc1.Cc1ccc(C(C)C)cc1.NCCN

TUCAN

C32H39ClFN7O2Ru/(1-41)(2-58)(3-41)(4-55)(5-58)(6-41)(7-59)(8-42)(9-44)(10-43)(11-48)(12-59)(13-42)(14-45)(15-40)(16-42)(17-66)(18-66)(19-66)(20-47)(21-64)(22-50)(23-67)(24-57)(25-63)(26-60)(27-67)(28-56)(29-60)(30-40)(31-40)(32-46)(33-49)(34-51)(35-72)(36-72)(37-73)(38-73)(39-75)(40-53)(41-55)(42-55)(43-44)(43-53)(44-52)(45-48)(45-53)(46-61)(46-71)(47-54)(47-68)(48-52)(49-51)(49-70)(50-62)(50-69)(51-61)(52-55)(54-62)(54-65)(56-57)(56-74)(57-76)(58-59)(58-72)(59-73)(60-67)(60-76)(61-75)(62-78)(63-74)(63-76)(64-77)(64-78)(65-75)(65-77)(66-79)(67-80)(68-69)(68-80)(69-79)(70-71)(70-81)(71-82)(77-83)(78-83)(79-83)(80-83)

Measurements (5)

Cell lineIC₅₀ dark (µM)IC₅₀ light (µM)DOIYear
A54924 10.1039/c5mt00122f 2015
A43131 10.1039/c5mt00122f 2015
MCF-773 10.1039/c5mt00122f 2015
PC-378 10.1039/c5mt00122f 2015
HeLa 10.1039/c5mt00122f 2015

🧬 Cell Death Types (1)

Apoptosis high
«complex 3 induced a large ratio of A549 cells early-stage apoptosis (56.8%)»