Info
| ID | 4672 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 0 |
| Donor atoms | {"N": 5} |
| Abbreviation | 3 |
| SMILES | COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCn1ccnc1.Cc1ccc(C(C)C)cc1.[Cl-].[Cl-] |
TUCAN
C30H31ClFN5O2Ru/(1-32)(2-34)(3-57)(4-32)(5-32)(6-33)(7-40)(8-50)(9-35)(10-36)(11-37)(12-38)(13-50)(14-53)(15-57)(16-34)(17-33)(18-34)(19-33)(20-47)(21-56)(22-56)(23-56)(24-49)(25-43)(26-39)(27-48)(28-54)(29-42)(30-41)(31-63)(32-47)(33-47)(34-45)(35-36)(35-45)(36-44)(37-38)(37-44)(38-45)(39-51)(39-61)(40-46)(40-58)(41-43)(41-60)(42-52)(42-59)(43-51)(44-47)(46-52)(46-55)(48-49)(48-62)(49-64)(50-57)(50-64)(51-63)(52-66)(53-62)(53-64)(54-65)(54-66)(55-63)(55-65)(56-68)(57-67)(58-59)(58-67)(59-68)(60-61)(60-69)(61-70)(65-71)(66-71)(67-71)(68-71)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 15 | — | 10.1039/c5mt00122f | 2015 |
| A431 | 32 | — | 10.1039/c5mt00122f | 2015 |
| MCF-7 | 54 | — | 10.1039/c5mt00122f | 2015 |
| PC-3 | 64 | — | 10.1039/c5mt00122f | 2015 |
| HeLa | — | — | 10.1039/c5mt00122f | 2015 |
🧬 Cell Death Types (1)
Apoptosis
high
«complex 3 induced a large ratio of A549 cells early-stage apoptosis (56.8%)»