Info
| ID | 4671 |
| Metal | Ru |
| Oxidation state | 2 |
| Charge | 1 |
| Donor atoms | {"N": 5} |
| Abbreviation | 2 |
| SMILES | COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCNCc1ccccn1.Cc1ccc(C(C)C)cc1.[Cl-] |
TUCAN
C34H37ClFN5O2Ru/(1-38)(2-40)(3-38)(4-38)(5-39)(6-60)(7-59)(8-41)(9-42)(10-44)(11-43)(12-59)(13-58)(14-60)(15-40)(16-39)(17-40)(18-49)(19-39)(20-53)(21-52)(22-53)(23-57)(24-51)(25-66)(26-66)(27-66)(28-64)(29-46)(30-47)(31-67)(32-45)(33-50)(34-67)(35-48)(36-73)(37-74)(38-57)(39-57)(40-55)(41-42)(41-55)(42-54)(43-44)(43-55)(44-54)(45-46)(45-58)(46-49)(47-56)(47-68)(48-63)(48-71)(49-61)(50-52)(50-63)(51-62)(51-69)(52-70)(53-60)(53-67)(54-57)(56-62)(56-65)(58-72)(59-61)(59-73)(60-73)(61-72)(62-76)(63-74)(64-75)(64-76)(65-74)(65-75)(66-78)(67-77)(68-69)(68-77)(69-78)(70-71)(70-79)(71-80)(75-81)(76-81)(77-81)(78-81)
Measurements (5)
| Cell line | IC₅₀ dark (µM) | IC₅₀ light (µM) | DOI | Year |
| A549 | 50 | — | 10.1039/c5mt00122f | 2015 |
| MCF-7 | 88 | — | 10.1039/c5mt00122f | 2015 |
| HeLa | — | — | 10.1039/c5mt00122f | 2015 |
| PC-3 | — | — | 10.1039/c5mt00122f | 2015 |
| A431 | — | — | 10.1039/c5mt00122f | 2015 |
🧬 Cell Death Types (1)
Apoptosis
high
«complex 3 induced a large ratio of A549 cells early-stage apoptosis (56.8%)»